advanced e-team

Lochlorine Chlorine Producer and Doser: Saving Lives Through Safe Water

University of California - Berkeley, 2009 - $20,000

Chlorination is a cheap and safe method to disinfect water that actively continues to disinfect for several days, unlike other methods that cannot guard against biological recontamination. Programs in the developing world using chlorination at the household level have seen water-borne illness decrease by 22-84%, but have faced logistical issues in reaching every home with a regular supply of chlorine and dosing errors that have led to under-chlorinated or over-chlorinated water. In Kenya, simple community chlorine dosers increased chlorine usage from 8-61%; however these dosers were limited in their ability to adapt to different volumes of water.

LoChlorine has developed two products, the LoChlorine Producer and LoChlorine Doser, both of which aim to safeguard family health by improving access to and the performance of chlorination. The LoChlorine Producer is a method that uses human power to produce chlorine locally that yields a reliable concentration of chlorine for pennies. The LoChlorine Doser is unique in its ability to automatically and appropriately dose arbitrary volumes of water. The design has no moving parts, uses no electricity, and could be mass-manufactured for less than ten dollars.

The team plans to implement the project initially in West Bengal, India, in partnership with the Aqua Welfare Society.

Don't Forget! Submission Deadline for Course & Program and Advanced E-Team Proposals: Friday, December 4, 2009

As the December deadline for Advanced E-Team and Course & Program grants rapidly approaches, we've interviewed Grants Manager Jennifer Keller Jackson on the common mistakes made when submitting grant proposals. Each of these podcasts is just a couple minutes. Worth a listen if you plan to submit a proposal!

Common Advanced E-Team Mistakes:

Common Course & Program Mistakes:

General Overview of NCIIA Grants Programs:

Have a grants-related question or topic you'd like to hear us talk about? Email us your ideas!

Bridging the gap

Two E-Teams talk about how they got venture capital funding—and the impact it made

One of the primary reasons the NCIIA is starting Venture Well is to address what you could call the “Big Gap”: the space between a group of college students working on an idea and a full-fledged venture worthy of investment. There’s a long way to go between the two, and it takes lots of hard work to get from one to the other. This summer we talked with two teams that succeeded in going from student E-Team to start-up to venture-funded company and discussed their journey through the world of early stage funding and venture capital.

How do you set yourself up to even be considered for venture capital funding? What are some of the pros and cons of taking equity financing? Their answers provide some good advice for prospective E-Teams.

The interviewees are both in the medical device field. Ashish Mitra was part of the Novel Aortic Endograft E-Team from Stanford, developers of a stent graft with an adhesive delivery platform. They went on to form Endoluminal Sciences and received $2 million in venture funding.

Evan Edwards, recipient of an E-Team grant in 2000, has been working toward commercializing his invention—a credit-card-sized epinephrine injector for people with severe allergies, dubbed the “EpiCard”—for the past eight years. His company, Intelliject, has received $13 million in venture funding and EpiCard is in late stages of development. Here are some highlights from the discussion.

How did you position yourselves for venture capital funding?

Edwards: The first step in moving toward VC funding is interacting with people. Talk with local businesses, join a venture group, join an on-campus entrepreneurship club. By going to their meetings and attending their seminars you’ll gain an understanding of how to write a business plan, or how to value your company, or how to do the financials; whatever you need. You’ll make your strengths even stronger and shore up your weaknesses. That will start you down the right path. Then you have to just get out there and see what they say. We made the rounds and presented the Intelliject business plan, and the feedback we received from the angels and VCs was very specific and very helpful. We re-worked the venture, then targeted VC firms that we thought would be excellent partners and obtained warm introductions.

Mitra: The first thing we concentrated on was the idea. Venture capitalists want big ideas with big potential returns, so we made sure we had a practicable, useful idea that addressed a huge unmet need. We made sure the need was validated by experts—physicians, engineers and VCs—and presented positive preliminary test data proving our concept.

What are some of the pros and cons of taking equity financing?

Edwards: On the plus side, you get smart money to help build the company, and you’re backed up by deep pockets if you need subsequent investment. The negative: big decisions need to be approved by the VC.

Mitra: For a university off-shoot like ours, the pros of equity financing far outweighed the cons. In fact, equity financing was really the only option given the R&D nature of the project and that none of the inventors/founders were in a position to support debt financing. VC funding not only enabled us to work under the mentorship of a highly experienced investor team but also helped us get to the point where we are moving to market faster. The obvious disadvantage with equity financing is the rate at which the shares of the founders are diluted over a period of time.

What would you recommend emerging E-Teams do to position themselves for major funding?

Edwards: The first thing is to get a great idea, put together a great team, and work hard on the idea and on interacting with people. Once you’re ready for the VCs, be targeted in your approach and evaluate VC firms carefully. Interview them as much as they interview you! Take a careful look at their domain expertise, their network, and their strategic thinking. Only do business with the firms that are right for you.

Mitra: My primary recommendation would be to involve a godfather—a star in the relevant area—right from the start. This will load the magazine of your pitching gun with words that tend to hit the bullseye of any investor pitch. The brighter the star, the more visible he or she should be on the team. One other piece of advice: investors pay much more attention to the team that will execute the project as compared to the team that invented it. The objective should not only be to convince them that the idea will work but also that the team can make it work.

*****

Both Mitra and Edwards agree that the the real work begins only after you receive major funding. Mitra needed to execute a multitude of tasks, from finding office space to hiring new employees, and Edwards used the money to finalize the product and move toward manufacturing. But both readily attest that the time and effort it takes to get VC funding is well worth it. The satisfactions, both mental and financial, can be substantial. And they’re both happy to get the chance to make a real difference in the world.

Featured articles

A collection of featured articles from NCIIA publications and newsletters

Waiting a while for the payoff: Insitutec

Imagine trying to bootstrap a company that makes industrial positioning and measuring systems with nanoscale resolution. Sound tough? It’s exactly what Shane and Bethany Woody, co-founders of Charlotte-based InsituTec, Inc., have been doing since incorporating in 2001... read more

 

The right team at the right time: Keen Mobility

Often, the best teams don’t form as a result of careful planning: good teams synthesize when the right people work on the right project at the right time. Such is the story of Vail Horton and the Keen Mobility E-Team... read more

Credit, Debit, or Cell Phone?

Imagine that you’re shopping at the supermarket. As you reach the end of the checkout line, the cashier offers you the familiar menu of choices with a new twist: “Credit, debit, or cell phone?”

Ajay Bam, founder of Boston-based mobile commerce processor Vayusa, Inc., and twice a recipient of NCIIA funding, wants to make this transaction a reality... read more

 

Different problems, same solution

It’s hard to go wrong when giving people access to new information: people crave it, markets need it, and the benefits often extend far beyond the initial application. Case in point: two Sustainable Vision grantees recently took a look at widely divergent problems and arrived at the same basic solution: these people need more information... read more

E-Team grantees focusing on new ways to meet residential energy needs

Even a brief look at the statistics regarding home energy consumption in the US can be staggering: American households consume 355 billion kwh per year for heating and cooling alone; US homes produce 21 percent of the country’s total global warming pollution; by 2020, the US residential sector will account for 11.4 quadrillion BTUs of end-use energy annually…In the long run, satisfying our energy needs while decreasing CO² emissions will require a coordinated effort on a number of fronts, including developing renewable energies and increasing energy efficiency.

Over the years, a number of NCIIA E-Teams have looked to do just that... read more

  Two E-Teams talk about how they got venture capital funding—and the impact it made

One of the primary reasons the NCIIA is starting Venture Well is to address what you could call the “Big Gap”: the space between a group of college students working on an idea and a full-fledged venture worthy of investment. There’s a long way to go between the two, and it takes lots of hard work to get from one to the other. This summer we talked with two teams that succeeded in going from student E-Team to start-up to venture-funded company and discussed their journey through the world of early stage funding and venture capital... read more

Student-run, their way: EcoTech Marine

Amid all the talk these days about elevator pitches and equity, burn rate and liquidation, preferred stock and venture fairs, we present to you one simple and reassuring fact: you don’t have to get fancy angel or VC funding to succeed. In fact, in certain situations you might be better off without it. Such is the story of EcoTech Marine, a team of students with enough entrepreneurial spirit and drive to take a product all the way to market themselves, with a minimum of private investment... read more

 

Marketing to the poor: International Development Enterprises (IDE)

Paul Polak didn’t have to do any of this. At age forty-seven, Polak was a successful Colorado psychiatrist with a wife, three daughters and $3 million in real estate. But in his extensive world travels Polak witnessed more and more the debilitating effects of extreme poverty on the world’s rural poor—who often make less than one dollar a day—and became curious about ways to help... read more
 

A failure success story: John Fabel

The story of John Fabel teaches us that when it comes to entrepreneurial endeavors, failure isn’t always a bad thing: new opportunities arise, lessons are learned, people move forward. In this profile we take you through John’s story, from invention to incorporation to bankruptcy to eventual success, and find out what he learned along the way... read more

 

Open to learn: Evan Edwards and EpiCard

Evan Edwards knows a thing or two about business plans. The recipient of an NCIIA Advanced E-Team grant in 2000, Edwards has been working toward commercializing his invention—a credit-card-sized epinephrine injector for people with severe allergies, dubbed the “EpiCard”—for the past few years. We spoke with Edwards about what goes into a business plan, the lessons he’s learned about writing them, and his advice for nascent inventors looking to build a company around a new technology... read more

Insulating your home with...mushrooms?

Open up the walls of just about any new home and you’ll find the same thing: two sheets of plywood sandwiching an insulating foam core. Known as Structural Insulating Panels, or SIPS, the approach is gaining popularity in the building industry because it’s cheap and effective. Unfortunately the foam insulation in SIPS is also environmentally damaging, requiring petroleum to produce, and it isn’t biodegradable, eventually ending up in landfills... read more

 

Whole Tree taking a wholly different approach

A standard approach to dealing with problems in the developing world is to develop a specific solution to a specific problem: if people lack access to potable water, you develop a water filter for them to buy and use. Need lighting? Manufacture and sell solar lamps. While there’s nothing wrong with this approach, Whole Tree, Inc., a former Baylor University E-Team and the first recipient of Venture Well investment funding (see sidebar on page 4), is using a different tactic: alleviating poverty by providing access to huge markets in the US and abroad... read more

Video stories

There's much to be learned from NCIIA's grantees. Enjoy these clips, and, visit our Youtube channel to see our favorites.

Insights from grantees Stories from the field

Advice for students

Paul Hudnut, Colorado State University

NCIIA support

Christie Chatterley, University of Colorado-Boulder

Sustainable Vision grants

Khanjan Mehta, Penn State

 

 

University of Colorado-Boulder: Developing a Replicable Model for Sustainable Technology Entrepreneurship in Afghanistan

Penn State: Mashavu: Networked Health Solutions for the Developing World

RPI: Greensulate (Ecovative Design)

University of Illinois at Urbana, Champaign: Greenlight Planet

 

 

 

 

 

Clean energy hits home, and more - NCIIA Fall Newsletter

Our fall newsletter is out. Clean energy in homes, new opportunities for faculty and students, 2010 Annual Conference and grantees from the May 2009 E-Team and Course and Program grants round. Read the newsletter here.

Cool tech file: Monitoring the 'health' of structures

When structures fail, the results can be catastrophic. Condition Engineering, a 2007 NCIIA E-Team grantee, designs systems that monitor the integrity of earthen infrastructure such as dams and levees, and the performance of air and space vehicles.

The technology: The SensorRope snakes down inside earthern structures and monitors the conditions of the structure, transmitting an early failure warning signal should the structural conditions be deemed dangerous. Condition Engineering is also developing a fiber optic sensing system for monitoring the temperature and structural integrity of high-temperature materials, such as a space vehicle's thermal protection shield.

The Breast Examination Simulator: A Training and Assessment Tool for Patrients and Physicians

Stanford University, 2001 - $16,700

Breast cancer is the second most common form of cancer among women in the US and the leading cause of cancer deaths for women. The National Cancer Institute estimates that one in eight American women will develop breast cancer in her lifetime. Early detection leads to early treatment and improved patient outcome. Breast Self-Exams (BSE) aid early discovery of the disease, but only 29% of women regularly conduct the exam. Part of the reason for this low percentage is that health care providers do not have a standardized method for teaching breast examination skills.

In response to this lack of uniformity, the Brest Examination Simulator E-Team developed training tools to simulate breast exams and teach the proper procedure. The team created computerized, strap-on breast models for teaching patients how to perform breast self-exams and plated breast models for teaching medical students, residents, nursing students, and physician assistants to perform clinical exams. Each model simulates various conditions, including normal and pathologic. Both models contain electronic sensors to communicate users' movements to a computer screen as they examine the models. The computer data provides individualized performance evaluations and helps define the quantitative and qualitative characteristics of an adequate clinical exam, thereby standardizing the method. Model development is based on the E-pelvis simulator, which one of the E-Team members designed.

The E-Team consisted of a business graduate student and two research associates, one with the Stanford University Medical Media and Information Technology Department and the other with the Department of Surgery. They worked with the owner of a hardware and software development company, a professor from the School of Medicine, and the president of Mentice Medical Stimulation AB, a simulator company.

Matrix NMR

Purdue University, 2001 - $16,000

Nuclear magnetic resonance (NMR) is an analytical tool for analyzing the molecular structure of a sample, including chemicals such as drugs, peptides, aromatic molecules, pesticides, food additives, and others. NMR experiments analyze complex samples such as blood and urine and help determine chemical information. NMR sets the standard for the analysis of new chemicals because it obtains different information from each atom in a sample with a nucleus-specific system. Though useful, slow speeds and high costs make NMR not commercially viable for some industries.

To remedy these problems, this E-Team from Purdue, comprised of three analytical chemistry Ph.D. candidates and a graduate researcher in the Technology Transfer Initiative, aimed to offer customers an improved NMR probe that significantly reduces the cost and time needed to perform NMR analysis. Instead of testing each sample serially, this team's technology tested them simultaneously. In addition, the technology required a smaller sample size.

Piggyback

Brown University, 2001 - $18,000

Medical professionals rely on a Personal Digital Assistant (PDA) for a number of daily tasks. PDAs replace medical dictionaries and encyclopedias by providing accurate, convenient reference information, and some PDAs perform as medical instruments, such as EKG monitoring devices. However, even as medical professionals benefit from PDA use, they still must fill out patient forms manually, often transcribing information from the reference software to their PDA. Medical professionals who do not wish to fill out charts by hand must leave their patients in order to retrieve printouts from desktop printers.

This E-Team recognized a need for more advanced technology to help medical professionals transfer information more efficiently from their PDA to patient evaluation forms. The team's solution consisted of a small printer that clips to the back of the PDA. The printer conforms to the shape of most PDAs and prints on both label and printer stock. Using label stock, medical professionals can print out information and affix it quickly and efficiently to patients' forms. Piggyback's printer also has the potential to incorporate additional components, such as Bluetooth, a wireless technology.

The team grew out of Brown University's Entrepreneurship course. The five undergraduates involved in the team had skills and knowledge in engineering, economics, entrepreneurship, computer science, and intellectual property. Two professors with extensive knowledge of engineering and intellectual property protection advised the team.

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